how to stay warm in your freezing bedroom:
put on a comfy sweater
put a sweatshirt on over it
put leggings on
put sweatpants on over them
4 pairs of fuzzy socks
light your bed on fire
and a partridge in a pear tree
"How much money does college cost in America?"
What Does the Spleen Do? ft. Harvard Medical School
That was do worth it
Scientists have a fresh idea for beating HIV: Target the virus with guided missiles called monoclonal antibodies.
At least in monkeys infected with an experimental virus similar to the human AIDS virus, the approach produced what researchers call “profound therapeutic efficacy.”
The virus plummeted to undetectable levels in animals that got potent antibodies of a type recently discovered in some humans with HIV. And the virus remained undetectable for weeks after a single antibody injection.
Most impressive, several monkeys who started out with low levels of HIV in their blood maintained extremely low levels of the virus in their systems months after a single antibody injection.
The researchers think they may have turned these animals into so-called elite controllers — like the 1 percent of HIV patients who are able to suppress the virus even without antiviral drugs.
The scientists say their results justify experiments in humans with HIV. And the potential implications seem to be large, in at least two ways:
- Periodic injections of monoclonal antibodies might be a new kind of treatment for HIV-infected humans, either alone or in combination with conventional antiviral drugs.
- Monoclonal antibodies might be incorporated into strategies, now being eagerly pursued by a number of scientists, to cure HIV infection — that is, to clear the virus from patients’ cells, allowing them to stop taking antiviral drugs.
"The findings of these two papers could revolutionize efforts to cure HIV," two cure-seekers write in a Nature commentary.
In the cryo-EM image of an HIV particle, the capsid surrounding the RNA-containing core is in red while the virus’s membrane is in blue. The yellow contains electron-dense material, including proteases. Credit: Stephen Fuller, Wellcome Images
It ain’t gonna suck itself
LUMPY SPACE PUG
guys… it’s that time of the year